Research library
Growth Hormone AxisPlausible but unproven in humans
GH releasing peptides
GHRP-2 / GHRP-6 / Hexarelin, Ghrelin mimetic GHRPs
A family of synthetic ghrelin mimetic GH releasing peptides acting on GHS-R1a, varying in GH potency, appetite stimulation, and cortisol/prolactin effect.
GHS-R1a
Cortisol / PRL
How GHRP-2 / GHRP-6 / Hexarelin works
A family of synthetic ghrelin mimetic peptides that switch on the GHS-R1a receptor to release growth hormone, with varying appetite and cortisol effects.
GHRP
GHS-R1a
GH release
↑ IGF-1
Research applications
GH release
Clinical pharmacology
Appetite (GHRP-6)
Stimulation
Bars indicate how far the evidence has progressed (in vitro to animal to human), not the size of any effect.
Evidence, safety & status
Claimed benefits & evidence
GH release, appetite (GHRP-6), and recovery are claimed. Human efficacy/safety for anti aging or performance is not established, though older clinical pharmacology studies confirm GH release.
Safety & dangers
Cortisol/prolactin elevation, water retention, IGF-1 mediated theoretical risks, and receptor desensitization (hexarelin).
Regulatory status
Not FDA approved; WADA prohibited (S2, GHRPs including hexarelin, GHRP-2/pralmorelin, and GHRP-6 explicitly named).
Source: Fnx Performance Peptide Research Database, a synthesis of the scientific and regulatory literature, not medical advice. For medical questions, consult a qualified physician.
For research use only
For Research Use Only. Not for human or animal consumption. Products are sold strictly for in vitro laboratory research, not for compounding or therapeutic application.