Research library
Longevity & MitochondrialPreclinical / anecdotal
EDR (Glu-Asp-Arg)
Pinealon, Tripeptide bioregulator
A short chain tripeptide bioregulator (Glu-Asp-Arg) from the Khavinson program, studied for neuroprotection and a proposed, but under validated, direct gene promoter binding mechanism.
Glu-Asp-Arg
Neural cells
0
How Pinealon works
An ultrashort tripeptide bioregulator studied for protecting neurons, with a striking, under validated claim that it binds DNA directly to tune gene expression.
Pinealon
Cell + nucleus
Gene promoters
Neuroprotection
Research applications
Neuroprotection
Oxidative stress reduction
Cognition / TBI
Memory support
Circadian / sleep
Marketed claim
Bars indicate how far the evidence has progressed (in vitro to animal to human), not the size of any effect.
Molecular profile
Evidence, safety & status
Claimed benefits & evidence
Marketed for neuroprotection, cognition, and circadian/sleep support. Carries the same single network limitation as Epitalon and BPC-157, essentially all evidence is from Khavinson's group. PubMed returns no completed peer reviewed RCTs; a Russian observational TBI study and rodent learning data exist. The DNA promoter binding mechanism is the most cited and least clinically validated part of the story.
Safety & dangers
No significant adverse effects in the thin (mostly preclinical/Russian) literature, but human safety is effectively uncharacterized, no PK, toxicology, or long term data. Theoretical concern of unknown off target gene effects.
Contraindications
Pregnancy; active malignancy (theoretical); anyone unable to verify product quality.
Regulatory status
Not FDA approved; research use only / gray market. Often paired commercially with Epitalon as a 'Russian longevity stack.' WADA: S0.
Administration
Subcutaneous or intranasal, short courses. Oral bioavailability is very poor.
Source: Fnx Performance Peptide Research Database, a synthesis of the scientific and regulatory literature, not medical advice. For medical questions, consult a qualified physician.
For research use only
For Research Use Only. Not for human or animal consumption. Products are sold strictly for in vitro laboratory research, not for compounding or therapeutic application.